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Contact Information
Name  
Hanhua HU
Academic Title  
  Professor
Education  
  Ph.D.
Phone  
  86-27-68780078
 E-mail 
  hanhuahu@ihb.ac.cn

Personal Profile:

Personal Data:  

Hanhua Hu, Male, obtained his PhD from Institute of Hydrobiology, Chinese Academy of Sciences (CAS) in 2001, and then joined School of life sciences, Xiamen University in August 2001 as Assistant Professor. From January 2002 to February 2004 he carried out his post-doctoral training at Institute of Process Engineering, Chinese Academy of Sciences. In March 2004 he became an associate professor at Institute of Hydrobiology, Chinese Academy of Sciences. From January 2008 to January 2010, he worked as a visiting scholar/Postdoc in the Département de biologie at école normale supérieure (Paris, France) conducting research in diatom biology. From July 2011 he built a research group at the Institute of Hydrobiology for diatom biology study. 

 

Research Experience: 

Mar. 2004 –Present: Diatom and Antarctic Microalgae Biology, Institute of Hydrobiology, CAS 

Jan. 2008 – Jan. 2010: Visiting scholar, Diatom Molecular Biology, Département de Biologie, école Normale Supérieure (Paris, France) 

Jan. 2002 – Feb. 2004: Postdoc, Red Tide Algae, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, CAS 

Aug. 2001 – Feb. 2004: Assistant Professor, Algal Physiology, School of Life Sciences, Xiamen University 


Research Directions:

Diatom Biology; Adaptive Evolution of Antarctic Microalgae; Utilization of Microalgae as Biodiesel

 
Social Titles:

Awards & Honors:
Recent Publications:

1. Rastogi A, Vieira FRJ, Deton-Cabanillas A-F, Veluchamy A, Cantrel C, Wang G, Vanormelingen P, Bowler C, Piganeau G, Hu H*, Tirichine L*. A genomics approach reveals the genetic polymorphism, structure and functional diversity of ten accessions of the diatom Phaeodactylum tricornutum. The ISME Journal. 2020, 14: 347-363. (*Corresponding author)

2. Chen Y, Hu H*. High efficiency transformation by electroporation of the freshwater alga Nannochloropsis limnetica. World Journal of Microbiology & Biotechnology. 2019, 35(8): 119.

3.  Li X, Pan Y, Hu H*. Identification of the triacylglycerol lipase in the chloroplast envelope of the diatom Phaeodactylum tricornutum. Algal Research. 2018, 33: 440-447.

4. Pan Y, Yang J, Gong Y, Li X, Hu H*. 3-hydroxyisobutyryl-CoA hydrolase involved in isoleucine catabolism regulates triacylglycerol accumulation in Phaeodactylum tricornutum. Philosophical Transactions of the Royal Society B‐Biological Sciences. 2017, 372(1728): 20160409.

5. Schoefs B*, Hu H*, Kroth PG*. The peculiar carbon metabolism in diatoms. Philosophical Transactions of the Royal Society B‐Biological Sciences. 2017, 372(1728): 20160405.

6. Wei L, Xin Y, Wang Q, Yang J, Hu H*, Xu J*. RNAi-based targeted gene-knockdown in the model oleaginous microalgae Nannochloropsis oceanica. The Plant Journal. 2017, 89(6): 1236-1250.

7. Yang J, Pan Y, Bowler C, Zhang L, Hu H*. Knockdown of phosphoenolpyruvate carboxykinase increases carbon flux to lipid synthesis in Phaeodactylum tricornutum. Algal Research. 2016, 15: 50-58.

8. Ge F, Huang W, Chen Z, Zhang C, Xiong Q, Bowler C, Yang J, Xu J, Hu H*. Methylcrotonyl-CoA carboxylase regulates triacylglycerol accumulation in the model diatom Phaeodactylum tricornutum. The Plant Cell. 2014, 26(4): 1681-1697.

9. Zhang C, Hu H*. High-efficiency nuclear transformation of the diatom Phaeodactylum tricornutum by electroporation. Marine Genomics. 2014, 16: 63-66.

10. Gong Y, Hu H*. Effect of silicate and inorganic carbon availability on the growth and competition of a diatom and two red-tide dinoflagellates. Phycologia. 2014, 53(5): 433-442.

11. Li F, Gao D, Hu H*. High-efficiency nuclear transformation of the oleaginous marine Nannochloropsis species using PCR product. Bioscience Biotechnology and Biochemistry. 2014, 78(5): 812-817.

12. Gong Y, Wan X, Jiang M, Hu C, Hu H, Huang F. Metabolic engineering of microorganisms to produce omega-3 very long-chain polyunsaturated fatty acids. Progress in Lipid Research. 2014, 56: 19-35.

13. Xu J, Hu H*. Screening high oleaginous Chlorella strains from different climate zones. Bioresource Technology. 2013, 144: 637-643.

14. Zha S, Xu X, Hu H*. A high sensitivity iron-dependent bioreporter used to measure iron bioavailability in freshwaters. FEMS Microbiology Letters. 2012, 334(2): 135-142.

15. Chen Z, He C, Hu H*. Temperature responses of growth, photosynthesis, fatty acid and nitrate reductase in Antarctic and temperate Stichococcus. Extremophiles. 2012, 16(1): 127-133.

16. Allen AE, Dupont CL, Oborník M, Horák A, Nunes-Nesi A, McCrow JP, Zheng H, Johnson DA, Hu H, Fernie AR, Bowler C. Evolution and metabolic significance of the urea cycle in photosynthetic diatoms. Nature. 2011, 473(7346): 203-207.

17. Hu H*, Zhang J, Chen W. Competition of bloom-forming marine phytoplankton at low nutrient concentrations. Journal of Environmental Sciences. 2011, 23(4): 656-663.

18. Maumus F, Allen AE, Mhiri C, Hu H, Jabbari K, Vardi A, Grandbastien M-A, Bowler C. Potential impact of stress activated retrotransposons on genome evolution in a marine diatom. BMC Genomics. 2009, 10: 624.

19. Hu H*, Li H, Xu X. Alternative cold response modes in Chlorella (Chlorophyta, Trebouxiophyceae) from Antarctica. Phycologia. 2008, 47(1): 28-34.

20. Zhang X, Hu H*, Tan T. Photosynthetic inorganic carbon utilization of gametophytes and sporophytes of Undaria pinnatifida (Phaeophyceae). Phycologia. 2006, 45(6): 642-647.

21. Hu H*, Chen W, Shi Y, Cong W. Nitrate and phosphate supplementation to increase toxin production by the marine dinoflagellate Alexandrium tamarense. Marine Pollution Bulletin. 2006, 52(7): 756-760.

22. Hu H*, Gao K. Response of growth and fatty acid compositions of Nannochloropsis sp. to environmental factors under elevated CO2 concentration. Biotechnology Letters. 2006, 28(13): 987-992.

23. Hu H*, Shi Y, Cong W. Improvement in growth and toxin production of Alexandrium tamarense by two-step culture method. Journal of Applied Phycology. 2006, 18(2): 119-126.

24. Shi Y, Hu H*, Cong W. Positive effects of continuous low nitrate levels on growth and photosynthesis of Alexandrium tamarense (Gonyaulacales, Dinophyceae). Phycological Research. 2005, 53(1): 43-48.

25. Shi Y, Hu H*, Ma R, Cong W, Cai Z. Improved use of organic phosphate by Skeletonema costatum through regulation of Zn2+ concentrations. Biotechnology Letters. 2004, 26(9): 747-751.

26. Hu H*, Shi Y, Cong W, Cai Z. Growth and photosynthesis limitation of marine red tide alga Skeletonema costatum by low concentrations of Zn2+. Biotechnology Letters. 2003, 25(22): 1881-1885.

27. Hu H, Gao K. Optimization of growth and fatty acid composition of a unicellular marine picoplankton, Nannochloropsis sp., with enriched carbon sources. Biotechnology Letters. 2003, 25(5): 421-425.


Grants & Research Projects: