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姓 名:
 甘南琴
性 别:
 女
职 称:
 研究员
学 历:
 研究生
电 话:
 86-27-68780210
电子邮件:
 gannq@ihb.ac.cn

简历:

  1971年生,博士,博士生导师/研究员,1996年毕业于河南师范大学,获学士学位;2002年毕业于武汉大学,获理学博士学位;2002年到中国科学院水生生物研究所工作;2007-2009于美国乔治敦大学(Georgetown University)做博士后研究;2011-2012年于美国加州大学河滨(California University Riverside)分校做访问研究;2011年在中国科学院水生生物研究所被聘为研究员。 

    围绕水华蓝藻及其毒素开展了系列工作,在微囊藻群体形成及维持、蓝藻毒素生物学功能、蓝藻毒素分析技术等方面取得了较为系统深入的研究结果。在J Biol. Chem., Environ. Microbiol., Appl. & Environ. Microbiol., Water Research, Carcinogenesis, Chem. Res. Toxicol., Toxicol. and Appl. Pharmacol.等国际重要期刊发表研究论文50余篇。获得国家授权专利4项。执笔起草国家标准2项(水中微囊藻毒素的测定,GB/T 20466-2006 水产品中微囊藻毒素的测定,GB 5009.XXX-201X)。

研究方向:

  蓝藻毒素分子毒理学; 蓝藻毒素生物功能学 


专家类别:

职务:

社会任职:

获奖及荣誉:
代表论著:

  1、 Nian Wei, Lili Hu, Lirong Song*, Nanqin Gan*. Microcystin-bound protein patterns in different cultures of Microcystis aeruginosa and field samples .toxins. 2016, 8(10), 293. 

  2、 Haiyan Ma, Yanlong Wu, Nanqin Gan, Lingling Zheng, Tianli Li, Lirong Song, Growth inhibitory effect of Microcystis on Aphanizomenon flos-aquae isolated from cyanobacteria bloom in Lake Dianchi, China, Harmful Algae, 2015 (42), 43-51 

  3、 Suqin Wang, Lin Zhu, Qi Li, Genbao Li*, Lin Li, Lirong Song, Nanqin Gan*, Distribution and population dynamics of potential anatoxin-a-producing cyanobacteria in Lake Dianchi, China, Harmful algae, 2015,48:63-68 

  4、 Lin Zhu, Yanlong Wu, Lirong Song, Nanqin Gan*, Ecological dynamics of toxic microcystis spp. and microcystin-degrading bacteria in Dianchi Lake, China. Appl. Environ. Microbiol., 2014, 80(6): 1874-1881.  

  5、 Cai Q, Fu L, Wang Z, Gan N, Dai X, Wang Y, α-N-methylation of damaged DNA-binding protein 2 (DDB2) and its function in nucleotide excision repair, J Biol Chem. 2014 Jun 6;289(23):16046-56.  

  6、 Wu Y, Li L, Gan N, Zheng L, Ma H, Shan K, Liu J, Xiao B, Song L. Seasonal dynamics of water bloom-forming Microcystis morphospecies and the associated extracellular microcystin concentrations in large, shallow, eutrophic Dianchi Lake. J Environ Sci (China). 2014 Sep;26(9):1921-9. 

  7、 Nanqin Gan, Yan Xiao, Lin Zhu, Zhongxing Wu, Jing Liu, Lirong Song, The role of microcystins in maintaining colonies of bloom-forming Microcystis spp. Environmental Microbiology, 201214(3): 730-742 

  8、 Nanqin Gan, Sun Xiaoyun, Lirong Song. Activation of Nrf2 by Microcystin-LR and provides advantages for liver cancer cell growth. Chem. Res. Toxicol., 2010 23 (9), 14771484. 

  9、 Nanqin Gan, Lixin Mi, Xiaoyun Sun, Guofei Dai, Fung-Lung Chung, Lirong Song. Sulforaphane Protects Microcystin-LR-Induced toxicity through Activation of the Nrf2-Mediated Defensive Response. Toxicology and Applied Pharmacology, 2010, 247: 129-137. 

  10、Nanqin Gan, Mathilde Brunet, Carmen Garrido, Fung-Lung Chung, Lixin MiSulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Upregulation of Hsp27J Biol. Chem., 2010, 285: 35528-35536. 

  11、Lin Zhu, Yanlong Wu, Lirong Song, Nanqin Gan*, Ecological dynamics of the toxic microcystis spp. and microcystin degrading bacteria in Dianchi Lake, Appl. Environ. Microbiol., 2014, 80(6): PMID: 24413601. 

  12、Lixin Mi, Nanqin Gan, Amrita Cheema, Sivanesan Dakshanamurthy, Xiantao Wang, David C. H. Yang, Fung-Lung Chung. Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes. J. Biol. Chem. 2009, 284: 17039-17051. 

  13、Guofei Dai, Changyun Quan, Xianzheng Zhang, Lirong Song, Nanqin Gan*, Fast removal of cyanobacterial toxin MC-LR by low-cytotoxic microgel-Fe3+ complexWater Research, 2012, 46(5):1482-1489. 

  14、Xiaoyun Sun, Lixin Mi, Lirong Song, Nanqin Gan*, Protection against Microcystin-LR-Induced hepatotoxicity by Sulforaphane in BALB/c mice, Toxicology and applied Pharmacology, 2011, 255, 9-17. 

  15、Chenlin Hu, Nanqin Gan, Yuanyuan Chen, Lijun Bi, Xianen Zhang, Lirong Song, Detection of microcystins in environmental samples using surface plasmon resonance biosensor. Talanta, 2009, 80:407410. 

  16、Lixin Mi, Nanqin Gan, Fung-Lung Chung, Isothiocyanates Inhibit Proteasome Activity and Proliferation of Multiple Myeloma Cells. Carcinogenesis, 2011, 32 (2):216-23. 

  17、Yan Xiao, Nanqin Gan, Jin Liu, Lirong Song, Heterogeneity of buoyancy in response to light between two buoyant types of cyanobacterium Microcystis, Hydrobiol., 2012, 679, 297-311. 

  18、Yi Ding, Nanqin Gan, Jie Li, Bojan Sedmak, Lirong Song, Hydrogen peroxide induces apoptotic-like cell death in Microcystis aeruginosa (Chroococcales, Cyanobacteria) in a dose-dependent manner, Phycologia, 2012, 51 (5), 567575. 

  19、Jie Li, Danyun Ou, Lingling Zheng, Nanqin Gan and Lirong Song. Applicability of the fluorescein diacetate assay for metabolic activity measurement of Microcystis aeruginosa (Chroococcales, Cyanobacteria). Phycological Research, 2011, 59: 200207. 

  20、Nanqin Gan, Qun Huang, Lingling Zheng, Lirong Song, Quantitative assessment of toxic and nontoxic Microcystis colonies in natural environments using fluorescence in situ hybridization and flow cytometry. Science in China (Series C: Life Sciences), 2010, 538):973-980. 

  21、Lixin Mi, Paul Sirajuddin, Nanqin Gan, Xiantao Wang, A cautionary note on using N-acetylcysteine as an antagonist to assess isothiocyanate-induced reactive oxygen species-mediated apoptosis. Anal. Biochem. 2010, 405 (2):269-71. 

  22、Lixin Mi, Nanqin Gan, Fung-Lung Chung. Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery. Biochemical and Biophysical Research Communications, 2009, 388: 456-462. 

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